Authorization from the state of California CDPH for exotic vector use
NDA Penn state and UC Irvine
UCSD Shipping Permits
john Hopkins to UC, Irvine Interstate movement. A. Gambiae docking sites USDA interstate movement permit application preliminary review
USDA permits
MIT cheat sheet for permitting biological materials
Permits and Field work
Duke Permits and Procedures for Field work
Guidelines for Shipping/Receiving Biological Materials
Permit to Import or Transport Etiologic Hosts or Vectors of Human Disease | Required for importation, interstate and intrastate transport of human pathogens. Expedites the package through customs.
Contact: Centers for Disease Control and Prevention at 404-718-2093. | Materials such as blood, bodily fluid, animals, etc that come from areas of endemic infection should be permitted.
Takes 2 weeks to process, expires after movement of material occurs,
Examples of materials for permit: blood, serum or plasma from different countries unless verified to be virus free, dengue, |
https://www.aphis.usda.gov/aphis/resources/permits
Apply for ePermit access and authenticate. You may need to authenticate in person.
Fill out online questionnaire according to permit type and submit,. You can check status https://www.aphis.usda.gov/aphis/ourfocus/biotechnology/sa_permits_notifications_and_petitions/sa_check_status
sample of status check
FDA and EPA would be for live mosquitoes. The constructs should go through IBC and EHS locally, IATA...etc.
As of January 2017 the FDA defines GMO Mosquitoes as;
1. Examples of New Animal Drugs a. Products intended to reduce the virus/pathogen load within a mosquito, including reduction in virus/pathogen replication and spread within the mosquito and/or reduction in virus/pathogen transmissibility from mosquitoes to humans. b. Products intended to prevent mosquito-borne disease in humans or animals. (FDA)
It recommends approvals from both agencies (FDA and EPA) to assure due diligence.
2. Example of Pesticide Products a. Products intended to reduce the population of mosquitoes (for example, by killing them at some point in their life cycle, or by interfering with their reproduction or development)5 . (EPA)
UCI IRB does not have specific guidance for GMO mosquitoes, however it would expect documentation of community consent prior to any release.
You can email your approved documents to: UCI-Malaria-Initiative@uci.edu